Regitin Methanesulphonate
Brand names,
Regitin Methanesulphonate
Analogs
Regitin Methanesulphonate
Brand Names Mixture
Regitin Methanesulphonate
Chemical_Formula
C17H19N3O
Regitin Methanesulphonate
RX_link
http://www.rxlist.com/cgi/generic3/phentol.htm
Regitin Methanesulphonate
fda sheet
Regitin Methanesulphonate
msds (material safety sheet)
Regitin Methanesulphonate
Synthesis Reference
No information avaliable
Regitin Methanesulphonate
Molecular Weight
281.352 g/mol
Regitin Methanesulphonate
Melting Point
174.5 oC
Regitin Methanesulphonate
H2O Solubility
No information avaliable
Regitin Methanesulphonate
State
Solid
Regitin Methanesulphonate
LogP
2.551
Regitin Methanesulphonate
Dosage Forms
Liquid
Regitin Methanesulphonate
Indication
For the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine. Also for the prevention or control of hypertensive episodes that may occur in a patient with pheochromocytoma as a result of stress or manipulation during preoperative preparation and surgical excision.
Regitin Methanesulphonate
Pharmacology
Phentolamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phentolamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phentolamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phentolamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.
Regitin Methanesulphonate
Absorption
No information avaliable
Regitin Methanesulphonate
side effects and Toxicity
No information avaliable
Regitin Methanesulphonate
Patient Information
No information avaliable
Regitin Methanesulphonate
Organisms Affected
Humans and other mammals