Regitine
Regitine Brand names, Regitine Analogs
Regitine Brand Names Mixture
- No information avaliable
Regitine Chemical_Formula
C17H19N3O
Regitine RX_link
http://www.rxlist.com/cgi/generic3/phentol.htm
Regitine fda sheet
Regitine msds (material safety sheet)
Regitine Synthesis Reference
No information avaliable
Regitine Molecular Weight
281.352 g/mol
Regitine Melting Point
174.5 oC
Regitine H2O Solubility
No information avaliable
Regitine State
Solid
Regitine LogP
2.551
Regitine Dosage Forms
Liquid
Regitine Indication
For the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine. Also for the prevention or control of hypertensive episodes that may occur in a patient with pheochromocytoma as a result of stress or manipulation during preoperative preparation and surgical excision.
Regitine Pharmacology
Phentolamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phentolamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phentolamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phentolamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.
Regitine Absorption
No information avaliable
Regitine side effects and Toxicity
No information avaliable
Regitine Patient Information
No information avaliable
Regitine Organisms Affected
Humans and other mammals
