Regitine

• Antihypertensive Agents
• Sympatholytics
• ATC:C04AB01
• ATC:G04BE05

• Phenotolamine
• Phentalamine
• Phentolamine Mesilate
• Phentolamine Mesylate
• Phentolamine Mesylate [USAN]
• Phentolamine Methanesulfonate
• Phentolamine Methanesulphonate
• Phentolamine, Methyl Sulfonate
• Regitin
• Regitin Methanesulphonate
• Regitine
• Regitine Mesylate
• Regitine Methanesulfonate
• Regitipe
• Rogitine

• No information avaliable

C₁₇H₁₉N₃O

http://www.rxlist.com/cgi/generic3/phentol.htm

No information avaliable

281.352 g/mol

174.5 ^oC

No information avaliable

Solid

2.551

Liquid

For the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine. Also for the prevention or control of hypertensive episodes that may occur in a patient with pheochromocytoma as a result of stress or manipulation during preoperative preparation and surgical excision.

Phentolamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phentolamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phentolamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phentolamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.

No information avaliable

No information avaliable

No information avaliable

Humans and other mammals