Pfizer)
Pfizer) Brand names, Pfizer) Analogs
- GH
- GH-N
- Growth hormone
- Growth hormone 1
- Pituitary growth hormone
- Somatotropin precursor
- BioTropin (Biotech General)
- Genotropin (Pharmacia
- Humatrope (Eli Lilly)
- Norditropin (Novo Nordisk)
- Nutropin (Genentech Inc.)
- NutropinAQ (Genentech Inc.)
- Pfizer)
- Protropin (Genentech Inc.)
- Saizen (Serono SA)
- Serostim (Serono SA)
- Tev-Tropin (GATE)
Pfizer) Brand Names Mixture
- No information avaliable
Pfizer) Chemical_Formula
C990H1532N262O300S7
Pfizer) RX_link
http://www.rxlist.com/cgi/generic3/nutropin.htm
Pfizer) fda sheet
Pfizer) msds (material safety sheet)
Pfizer) Synthesis Reference
No information avaliable
Pfizer) Molecular Weight
22129.0
Pfizer) Melting Point
76 oC at pH 3.5 (Gomez-Orellana, I. et al., Protein Sci. 7:1352-1358 (1998).
Pfizer) H2O Solubility
No information avaliable
Pfizer) State
Liquid
Pfizer) LogP
-0.411
Pfizer) Dosage Forms
Solution (Subcutaneous Injection); Powder for solution
Pfizer) Indication
For treatment of dwarfism, acromegaly and prevention of HIV-induced weight loss
Pfizer) Pharmacology
Used in the treatment of dwarfism and growth failure, growth hormone (hGH) stimulates skeletal growth in pediatric patients with growth failure due to a lack of adequate secretion of endogenous GH. Skeletal growth is accomplished at the epiphyseal plates at the ends of a growing bone. Growth and metabolism of epiphyseal plate cells are directly stimulated by GH and one of its mediators, IGF-I (insulin-like growth factor).
Pfizer) Absorption
No information avaliable
Pfizer) side effects and Toxicity
No information avaliable
Pfizer) Patient Information
BIOD00086.html
Pfizer) Organisms Affected
Humans and other mammals
