Saizen (Serono SA)
Brand names,
Saizen (Serono SA)
Analogs
Saizen (Serono SA)
Brand Names Mixture
Saizen (Serono SA)
Chemical_Formula
C990H1532N262O300S7
Saizen (Serono SA)
RX_link
http://www.rxlist.com/cgi/generic3/nutropin.htm
Saizen (Serono SA)
fda sheet
Saizen (Serono SA)
msds (material safety sheet)
Saizen (Serono SA)
Synthesis Reference
No information avaliable
Saizen (Serono SA)
Molecular Weight
22129.0
Saizen (Serono SA)
Melting Point
76 oC at pH 3.5 (Gomez-Orellana, I. et al., Protein Sci. 7:1352-1358 (1998).
Saizen (Serono SA)
H2O Solubility
No information avaliable
Saizen (Serono SA)
State
Liquid
Saizen (Serono SA)
LogP
-0.411
Saizen (Serono SA)
Dosage Forms
Solution (Subcutaneous Injection); Powder for solution
Saizen (Serono SA)
Indication
For treatment of dwarfism, acromegaly and prevention of HIV-induced weight loss
Saizen (Serono SA)
Pharmacology
Used in the treatment of dwarfism and growth failure, growth hormone (hGH) stimulates skeletal growth in pediatric patients with growth failure due to a lack of adequate secretion of endogenous GH. Skeletal growth is accomplished at the epiphyseal plates at the ends of a growing bone. Growth and metabolism of epiphyseal plate cells are directly stimulated by GH and one of its mediators, IGF-I (insulin-like growth factor).
Saizen (Serono SA)
Absorption
No information avaliable
Saizen (Serono SA)
side effects and Toxicity
No information avaliable
Saizen (Serono SA)
Patient Information
BIOD00086.html
Saizen (Serono SA)
Organisms Affected
Humans and other mammals