Growth hormone 1
Brand names,
Growth hormone 1
Analogs
Growth hormone 1
Brand Names Mixture
Growth hormone 1
Chemical_Formula
C990H1532N262O300S7
Growth hormone 1
RX_link
http://www.rxlist.com/cgi/generic3/somavert.htm
Growth hormone 1
fda sheet
Growth hormone 1
msds (material safety sheet)
Growth hormone 1
Synthesis Reference
No information avaliable
Growth hormone 1
Molecular Weight
22129.0
Growth hormone 1
Melting Point
76 oC at pH 3.5 (Gomez-Orellana, I. et al., Protein Sci. 7:1352-1358 (1998).
Growth hormone 1
H2O Solubility
No information avaliable
Growth hormone 1
State
Liquid
Growth hormone 1
LogP
-0.411
Growth hormone 1
Dosage Forms
Solution (Subcutaneous Injection); Powder
Growth hormone 1
Indication
For treatment of acromegaly
Growth hormone 1
Pharmacology
Somavert is used for the treatment of acromegaly, which arises from excessive IGF-1 levels. Somavert selectively binds to growth hormone (GH) receptors on cell surfaces, where it blocks the binding of endogenous GH, and thus interferes with GH signal transduction. Inhibition of GH action results in decreased serum concentrations of insulin-like growth factor-I (IGF-I), and IGF binding protein-3 (IGFBP-3). This reduces the symptoms of acromegaly.
Growth hormone 1
Absorption
No information avaliable
Growth hormone 1
side effects and Toxicity
No information avaliable
Growth hormone 1
Patient Information
BIOD00044.html
Growth hormone 1
Organisms Affected
Humans and other mammals