GH-N
GH-N Brand names, GH-N Analogs
GH-N Brand Names Mixture
- No information avaliable
GH-N Chemical_Formula
C990H1532N262O300S7
GH-N RX_link
http://www.rxlist.com/cgi/generic3/somavert.htm
GH-N fda sheet
GH-N msds (material safety sheet)
GH-N Synthesis Reference
No information avaliable
GH-N Molecular Weight
22129.0
GH-N Melting Point
76 oC at pH 3.5 (Gomez-Orellana, I. et al., Protein Sci. 7:1352-1358 (1998).
GH-N H2O Solubility
No information avaliable
GH-N State
Liquid
GH-N LogP
-0.411
GH-N Dosage Forms
Solution (Subcutaneous Injection); Powder
GH-N Indication
For treatment of acromegaly
GH-N Pharmacology
Somavert is used for the treatment of acromegaly, which arises from excessive IGF-1 levels. Somavert selectively binds to growth hormone (GH) receptors on cell surfaces, where it blocks the binding of endogenous GH, and thus interferes with GH signal transduction. Inhibition of GH action results in decreased serum concentrations of insulin-like growth factor-I (IGF-I), and IGF binding protein-3 (IGFBP-3). This reduces the symptoms of acromegaly.
GH-N Absorption
No information avaliable
GH-N side effects and Toxicity
No information avaliable
GH-N Patient Information
BIOD00044.html
GH-N Organisms Affected
Humans and other mammals
