Growth hormone
Brand names,
Growth hormone
Analogs
Growth hormone
Brand Names Mixture
Growth hormone
Chemical_Formula
C990H1532N262O300S7
Growth hormone
RX_link
http://www.rxlist.com/cgi/generic3/somavert.htm
Growth hormone
fda sheet
Growth hormone
msds (material safety sheet)
Growth hormone
Synthesis Reference
No information avaliable
Growth hormone
Molecular Weight
22129.0
Growth hormone
Melting Point
76 oC at pH 3.5 (Gomez-Orellana, I. et al., Protein Sci. 7:1352-1358 (1998).
Growth hormone
H2O Solubility
No information avaliable
Growth hormone
State
Liquid
Growth hormone
LogP
-0.411
Growth hormone
Dosage Forms
Solution (Subcutaneous Injection); Powder
Growth hormone
Indication
For treatment of acromegaly
Growth hormone
Pharmacology
Somavert is used for the treatment of acromegaly, which arises from excessive IGF-1 levels. Somavert selectively binds to growth hormone (GH) receptors on cell surfaces, where it blocks the binding of endogenous GH, and thus interferes with GH signal transduction. Inhibition of GH action results in decreased serum concentrations of insulin-like growth factor-I (IGF-I), and IGF binding protein-3 (IGFBP-3). This reduces the symptoms of acromegaly.
Growth hormone
Absorption
No information avaliable
Growth hormone
side effects and Toxicity
No information avaliable
Growth hormone
Patient Information
BIOD00044.html
Growth hormone
Organisms Affected
Humans and other mammals