Somatotropin precursor
Brand names,
Somatotropin precursor
Analogs
Somatotropin precursor
Brand Names Mixture
Somatotropin precursor
Chemical_Formula
C990H1532N262O300S7
Somatotropin precursor
RX_link
http://www.rxlist.com/cgi/generic3/somavert.htm
Somatotropin precursor
fda sheet
Somatotropin precursor
msds (material safety sheet)
Somatotropin precursor
Synthesis Reference
No information avaliable
Somatotropin precursor
Molecular Weight
22129.0
Somatotropin precursor
Melting Point
76 oC at pH 3.5 (Gomez-Orellana, I. et al., Protein Sci. 7:1352-1358 (1998).
Somatotropin precursor
H2O Solubility
No information avaliable
Somatotropin precursor
State
Liquid
Somatotropin precursor
LogP
-0.411
Somatotropin precursor
Dosage Forms
Solution (Subcutaneous Injection); Powder
Somatotropin precursor
Indication
For treatment of acromegaly
Somatotropin precursor
Pharmacology
Somavert is used for the treatment of acromegaly, which arises from excessive IGF-1 levels. Somavert selectively binds to growth hormone (GH) receptors on cell surfaces, where it blocks the binding of endogenous GH, and thus interferes with GH signal transduction. Inhibition of GH action results in decreased serum concentrations of insulin-like growth factor-I (IGF-I), and IGF binding protein-3 (IGFBP-3). This reduces the symptoms of acromegaly.
Somatotropin precursor
Absorption
No information avaliable
Somatotropin precursor
side effects and Toxicity
No information avaliable
Somatotropin precursor
Patient Information
BIOD00044.html
Somatotropin precursor
Organisms Affected
Humans and other mammals