Peridol
Brand names,
Peridol
Analogs
Peridol
Brand Names Mixture
Peridol
Chemical_Formula
C21H23ClFNO2
Peridol
RX_link
http://www.rxlist.com/cgi/generic/haloper.htm
Peridol
fda sheet
Peridol
msds (material safety sheet)
Peridol
Synthesis Reference
P. A. J. Janssen, Belg. pat. 577,977 (1959), C.A. 54, 4630c (1960); idem, Brit. pat. 895,309 corresp to U.S. pat. 3,438,991 (1962, 1969 to Janssen).
Peridol
Molecular Weight
375.864 g/mol
Peridol
Melting Point
151.5 oC
Peridol
H2O Solubility
14 mg/L
Peridol
State
Solid
Peridol
LogP
4.362
Peridol
Dosage Forms
Injection; Oral solution; Tablet
Peridol
Indication
For the treatment of schizophrenic patients who require prolonged parenteral antipsychotic therapy also used in Tourette's syndrome and Severe hyperactivity.
Peridol
Pharmacology
Haloperidol is a psychotropic agent indicated for the treatment of schizophrenia. It also exerts sedative and antiemetic activity. Haloperidol has actions at all levels of the central nervous system-primarily at subcortical levels-as well as on multiple organ systems. Haloperidol has strong antiadrenergic and weaker peripheral anticholinergic activity; ganglionic blocking action is relatively slight. It also possesses slight antihistaminic and antiserotonin activity.
Peridol
Absorption
Oral-60%
Peridol
side effects and Toxicity
LD50=165 mg/kg (rats, oral)
Peridol
Patient Information
PRD00538_PI.txt
Peridol
Organisms Affected
Humans and other mammals