Haldol Decanoate
Brand names,
Haldol Decanoate
Analogs
Haldol Decanoate
Brand Names Mixture
Haldol Decanoate
Chemical_Formula
C28H29F2N3O
Haldol Decanoate
RX_link
http://www.rxlist.com/cgi/generic3/orap.htm
Haldol Decanoate
fda sheet
Haldol Decanoate
msds (material safety sheet)
Haldol Decanoate
Synthesis Reference
No information avaliable
Haldol Decanoate
Molecular Weight
461.546 g/mol
Haldol Decanoate
Melting Point
214-218 oC
Haldol Decanoate
H2O Solubility
10 mg/L
Haldol Decanoate
State
Solid
Haldol Decanoate
LogP
5.761
Haldol Decanoate
Dosage Forms
Tablet
Haldol Decanoate
Indication
Used for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment.
Haldol Decanoate
Pharmacology
Pimozide is an orally active antipsychotic drug product which shares with other antipsychotics the ability to blockade dopaminergic receptors on neurons in the central nervous system. However, receptor blockade is often accompanied by a series of secondary alterations in central dopamine metabolism and function which may contribute to both pimozide's therapeutic and untoward effects. In addition, pimozide, in common with other antipsychotic drugs, has various effects on other central nervous system receptor systems which are not fully characterized. Pimozide also has less potential for inducing sedation and hypotension as it has more specific dopamine receptor blocking activity than other neuroleptic agents (and is therefore a suitable alternative to haloperidol).
Haldol Decanoate
Absorption
Greater than 50% absorption after oral administration. Serum peak appears 6-8 hours post ingestion.
Haldol Decanoate
side effects and Toxicity
LD50 = 1100 mg/kg (rat, oral), 228 mg/kg (mouse, oral)
Haldol Decanoate
Patient Information
No information avaliable
Haldol Decanoate
Organisms Affected
Humans and other mammals