Haldol
Brand names,
Haldol
Analogs
Haldol
Brand Names Mixture
Haldol
Chemical_Formula
C28H29F2N3O
Haldol
RX_link
http://www.rxlist.com/cgi/generic3/orap.htm
Haldol
fda sheet
Haldol
msds (material safety sheet)
Haldol
Synthesis Reference
No information avaliable
Haldol
Molecular Weight
461.546 g/mol
Haldol
Melting Point
214-218 oC
Haldol
H2O Solubility
10 mg/L
Haldol
State
Solid
Haldol
LogP
5.761
Haldol
Dosage Forms
Tablet
Haldol
Indication
Used for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment.
Haldol
Pharmacology
Pimozide is an orally active antipsychotic drug product which shares with other antipsychotics the ability to blockade dopaminergic receptors on neurons in the central nervous system. However, receptor blockade is often accompanied by a series of secondary alterations in central dopamine metabolism and function which may contribute to both pimozide's therapeutic and untoward effects. In addition, pimozide, in common with other antipsychotic drugs, has various effects on other central nervous system receptor systems which are not fully characterized. Pimozide also has less potential for inducing sedation and hypotension as it has more specific dopamine receptor blocking activity than other neuroleptic agents (and is therefore a suitable alternative to haloperidol).
Haldol
Absorption
Greater than 50% absorption after oral administration. Serum peak appears 6-8 hours post ingestion.
Haldol
side effects and Toxicity
LD50 = 1100 mg/kg (rat, oral), 228 mg/kg (mouse, oral)
Haldol
Patient Information
No information avaliable
Haldol
Organisms Affected
Humans and other mammals