Aloperidin
Brand names,
Aloperidin
Analogs
Aloperidin
Brand Names Mixture
Aloperidin
Chemical_Formula
C21H23ClFNO2
Aloperidin
RX_link
http://www.rxlist.com/cgi/generic/haloper.htm
Aloperidin
fda sheet
Aloperidin
msds (material safety sheet)
Aloperidin
Synthesis Reference
P. A. J. Janssen, Belg. pat. 577,977 (1959), C.A. 54, 4630c (1960); idem, Brit. pat. 895,309 corresp to U.S. pat. 3,438,991 (1962, 1969 to Janssen).
Aloperidin
Molecular Weight
375.864 g/mol
Aloperidin
Melting Point
151.5 oC
Aloperidin
H2O Solubility
14 mg/L
Aloperidin
State
Solid
Aloperidin
LogP
4.362
Aloperidin
Dosage Forms
Injection; Oral solution; Tablet
Aloperidin
Indication
For the treatment of schizophrenic patients who require prolonged parenteral antipsychotic therapy also used in Tourette's syndrome and Severe hyperactivity.
Aloperidin
Pharmacology
Haloperidol is a psychotropic agent indicated for the treatment of schizophrenia. It also exerts sedative and antiemetic activity. Haloperidol has actions at all levels of the central nervous system-primarily at subcortical levels-as well as on multiple organ systems. Haloperidol has strong antiadrenergic and weaker peripheral anticholinergic activity; ganglionic blocking action is relatively slight. It also possesses slight antihistaminic and antiserotonin activity.
Aloperidin
Absorption
Oral-60%
Aloperidin
side effects and Toxicity
LD50=165 mg/kg (rats, oral)
Aloperidin
Patient Information
PRD00538_PI.txt
Aloperidin
Organisms Affected
Humans and other mammals