Pentoxifylline
Brand names,
Pentoxifylline
Analogs
Pentoxifylline
Brand Names Mixture
Pentoxifylline
Chemical_Formula
C13H18N4O3
Pentoxifylline
RX_link
http://www.rxlist.com/cgi/generic/pentox.htm
Pentoxifylline
fda sheet
Pentoxifylline
msds (material safety sheet)
Pentoxifylline
Synthesis Reference
Mohler et al., U.S. Pat. 3,422,107 (1969)
Pentoxifylline
Molecular Weight
278.307 g/mol
Pentoxifylline
Melting Point
105oC
Pentoxifylline
H2O Solubility
77 mg/mL
Pentoxifylline
State
Solid
Pentoxifylline
LogP
No information avaliable
Pentoxifylline
Dosage Forms
Tablet (extended-release)
Pentoxifylline
Indication
For the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs.
Pentoxifylline
Pharmacology
Pentoxifylline, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Pentoxifylline
Absorption
No information avaliable
Pentoxifylline
side effects and Toxicity
LD50=1385 mg/kg(orally in mice)
Pentoxifylline
Patient Information
No information avaliable
Pentoxifylline
Organisms Affected
Humans and other mammals