PENTOXYPHYLINE
Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C13H18N4O3
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RX_link
http://www.rxlist.com/cgi/generic/pentox.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
Mohler et al., U.S. Pat. 3,422,107 (1969)
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Molecular Weight
278.307 g/mol
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Melting Point
105oC
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H2O Solubility
77 mg/mL
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State
Solid
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LogP
No information avaliable
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Dosage Forms
Tablet (extended-release)
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Indication
For the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs.
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Pharmacology
Pentoxifylline, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
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Absorption
No information avaliable
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side effects and Toxicity
LD50=1385 mg/kg(orally in mice)
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals