Pentoxyphylline
Brand names,
Pentoxyphylline
Analogs
Pentoxyphylline
Brand Names Mixture
Pentoxyphylline
Chemical_Formula
C13H18N4O3
Pentoxyphylline
RX_link
http://www.rxlist.com/cgi/generic/pentox.htm
Pentoxyphylline
fda sheet
Pentoxyphylline
msds (material safety sheet)
Pentoxyphylline
Synthesis Reference
Mohler et al., U.S. Pat. 3,422,107 (1969)
Pentoxyphylline
Molecular Weight
278.307 g/mol
Pentoxyphylline
Melting Point
105oC
Pentoxyphylline
H2O Solubility
77 mg/mL
Pentoxyphylline
State
Solid
Pentoxyphylline
LogP
No information avaliable
Pentoxyphylline
Dosage Forms
Tablet (extended-release)
Pentoxyphylline
Indication
For the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs.
Pentoxyphylline
Pharmacology
Pentoxifylline, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Pentoxyphylline
Absorption
No information avaliable
Pentoxyphylline
side effects and Toxicity
LD50=1385 mg/kg(orally in mice)
Pentoxyphylline
Patient Information
No information avaliable
Pentoxyphylline
Organisms Affected
Humans and other mammals