Oxpentifylline
Brand names,
Oxpentifylline
Analogs
Oxpentifylline
Brand Names Mixture
Oxpentifylline
Chemical_Formula
C13H18N4O3
Oxpentifylline
RX_link
http://www.rxlist.com/cgi/generic/pentox.htm
Oxpentifylline
fda sheet
Oxpentifylline
msds (material safety sheet)
Oxpentifylline
Synthesis Reference
Mohler et al., U.S. Pat. 3,422,107 (1969)
Oxpentifylline
Molecular Weight
278.307 g/mol
Oxpentifylline
Melting Point
105oC
Oxpentifylline
H2O Solubility
77 mg/mL
Oxpentifylline
State
Solid
Oxpentifylline
LogP
No information avaliable
Oxpentifylline
Dosage Forms
Tablet (extended-release)
Oxpentifylline
Indication
For the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs.
Oxpentifylline
Pharmacology
Pentoxifylline, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Oxpentifylline
Absorption
No information avaliable
Oxpentifylline
side effects and Toxicity
LD50=1385 mg/kg(orally in mice)
Oxpentifylline
Patient Information
No information avaliable
Oxpentifylline
Organisms Affected
Humans and other mammals