Pentoxifyllin
Brand names,
Pentoxifyllin
Analogs
Pentoxifyllin
Brand Names Mixture
Pentoxifyllin
Chemical_Formula
C13H18N4O3
Pentoxifyllin
RX_link
http://www.rxlist.com/cgi/generic/pentox.htm
Pentoxifyllin
fda sheet
Pentoxifyllin
msds (material safety sheet)
Pentoxifyllin
Synthesis Reference
Mohler et al., U.S. Pat. 3,422,107 (1969)
Pentoxifyllin
Molecular Weight
278.307 g/mol
Pentoxifyllin
Melting Point
105oC
Pentoxifyllin
H2O Solubility
77 mg/mL
Pentoxifyllin
State
Solid
Pentoxifyllin
LogP
No information avaliable
Pentoxifyllin
Dosage Forms
Tablet (extended-release)
Pentoxifyllin
Indication
For the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs.
Pentoxifyllin
Pharmacology
Pentoxifylline, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Pentoxifyllin
Absorption
No information avaliable
Pentoxifyllin
side effects and Toxicity
LD50=1385 mg/kg(orally in mice)
Pentoxifyllin
Patient Information
No information avaliable
Pentoxifyllin
Organisms Affected
Humans and other mammals