Pentoxyfylline
Brand names,
Pentoxyfylline
Analogs
Pentoxyfylline
Brand Names Mixture
Pentoxyfylline
Chemical_Formula
C13H18N4O3
Pentoxyfylline
RX_link
http://www.rxlist.com/cgi/generic/pentox.htm
Pentoxyfylline
fda sheet
Pentoxyfylline
msds (material safety sheet)
Pentoxyfylline
Synthesis Reference
Mohler et al., U.S. Pat. 3,422,107 (1969)
Pentoxyfylline
Molecular Weight
278.307 g/mol
Pentoxyfylline
Melting Point
105oC
Pentoxyfylline
H2O Solubility
77 mg/mL
Pentoxyfylline
State
Solid
Pentoxyfylline
LogP
No information avaliable
Pentoxyfylline
Dosage Forms
Tablet (extended-release)
Pentoxyfylline
Indication
For the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs.
Pentoxyfylline
Pharmacology
Pentoxifylline, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Pentoxyfylline
Absorption
No information avaliable
Pentoxyfylline
side effects and Toxicity
LD50=1385 mg/kg(orally in mice)
Pentoxyfylline
Patient Information
No information avaliable
Pentoxyfylline
Organisms Affected
Humans and other mammals