Durapental
Brand names,
Durapental
Analogs
Durapental
Brand Names Mixture
Durapental
Chemical_Formula
C13H18N4O3
Durapental
RX_link
http://www.rxlist.com/cgi/generic/pentox.htm
Durapental
fda sheet
Durapental
msds (material safety sheet)
Durapental
Synthesis Reference
Mohler et al., U.S. Pat. 3,422,107 (1969)
Durapental
Molecular Weight
278.307 g/mol
Durapental
Melting Point
105oC
Durapental
H2O Solubility
77 mg/mL
Durapental
State
Solid
Durapental
LogP
No information avaliable
Durapental
Dosage Forms
Tablet (extended-release)
Durapental
Indication
For the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs.
Durapental
Pharmacology
Pentoxifylline, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Durapental
Absorption
No information avaliable
Durapental
side effects and Toxicity
LD50=1385 mg/kg(orally in mice)
Durapental
Patient Information
No information avaliable
Durapental
Organisms Affected
Humans and other mammals