Pentamidine en es it fr

Pentamidine Brand names, Pentamidine Analogs

Pentamidine Brand Names Mixture

  • No information avaliable

Pentamidine Chemical_Formula


Pentamidine RX_link

Pentamidine fda sheet

Pentamidine msds (material safety sheet)

Pentamidine MSDS

Pentamidine Synthesis Reference

No information avaliable

Pentamidine Molecular Weight

340.42 g/mol

Pentamidine Melting Point

186.0 oC (decomposes)

Pentamidine H2O Solubility


Pentamidine State


Pentamidine LogP


Pentamidine Dosage Forms

Powder for solution

Pentamidine Indication

For the treatment of pneumonia due to Pneumocystis carinii.

Pentamidine Pharmacology

Pentamidine is an antiprotozoal agent. It is an aromatic diamidine, and is known to have activity against Pneumocystis carinii. The exact nature of its antiprotozoal action is unknown. in vitro studies with mammalian tissues and the protozoan Crithidia oncopelti indicate that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids and proteins. Little is known about the drug's pharmacokinetics. The medication is also useful in Leishmaniasis and in prophylaxis against sleeping sickness caused by Trypanosoma brucei gambiense. Hydration before treatment lessens the incidence and severity of side effects, which include liver or kidney dysfunction, hypertension, hypotension, hypoglycemia, hypocalemia, leukopenia, thrombcytopenia, anemia, and allergic reaction. It is generally well-tolerated.

Pentamidine Absorption

Absorbed poorly through the gastrointestinal tract and is usually administered parenterally.

Pentamidine side effects and Toxicity

Symptoms of overdose include pain, nausea, anorexia, hypotension, fever, rash, bad taste in mouth, confusion/hallucinations, dizziness, and diarrhea.

Pentamidine Patient Information

No information avaliable

Pentamidine Organisms Affected

Pneumocystis carinii