Pneumopent

Pneumopent Brand names, Pneumopent Analogs

Pneumopent Brand Names Mixture

No information avaliable

Pneumopent Chemical_Formula

C₁₉H₂₄N₄O₂

Pneumopent RX_link

http://www.rxlist.com/cgi/generic3/pentam.htm

Pneumopent fda sheet

Pneumopent msds (material safety sheet)

Pneumopent MSDS

Pneumopent Synthesis Reference

No information avaliable

Pneumopent Molecular Weight

340.42 g/mol

Pneumopent Melting Point

186.0 ^oC (decomposes)

Pneumopent H₂O Solubility

Complete

Pneumopent State

Solid

Pneumopent LogP

3.28

Pneumopent Dosage Forms

Powder for solution

Pneumopent Indication

For the treatment of pneumonia due to Pneumocystis carinii.

Pneumopent Pharmacology

Pentamidine is an antiprotozoal agent. It is an aromatic diamidine, and is known to have activity against Pneumocystis carinii. The exact nature of its antiprotozoal action is unknown. in vitro studies with mammalian tissues and the protozoan Crithidia oncopelti indicate that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids and proteins. Little is known about the drug's pharmacokinetics. The medication is also useful in Leishmaniasis and in prophylaxis against sleeping sickness caused by Trypanosoma brucei gambiense. Hydration before treatment lessens the incidence and severity of side effects, which include liver or kidney dysfunction, hypertension, hypotension, hypoglycemia, hypocalemia, leukopenia, thrombcytopenia, anemia, and allergic reaction. It is generally well-tolerated.

Pneumopent Absorption

Absorbed poorly through the gastrointestinal tract and is usually administered parenterally.

Pneumopent side effects and Toxicity

Symptoms of overdose include pain, nausea, anorexia, hypotension, fever, rash, bad taste in mouth, confusion/hallucinations, dizziness, and diarrhea.

Pneumopent Patient Information