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Pentamide Brand names, Pentamide Analogs

Pentamide Brand Names Mixture

  • No information avaliable

Pentamide Chemical_Formula


Pentamide RX_link

Pentamide fda sheet

Pentamide msds (material safety sheet)

Pentamide MSDS

Pentamide Synthesis Reference

No information avaliable

Pentamide Molecular Weight

340.42 g/mol

Pentamide Melting Point

186.0 oC (decomposes)

Pentamide H2O Solubility


Pentamide State


Pentamide LogP


Pentamide Dosage Forms

Powder for solution

Pentamide Indication

For the treatment of pneumonia due to Pneumocystis carinii.

Pentamide Pharmacology

Pentamidine is an antiprotozoal agent. It is an aromatic diamidine, and is known to have activity against Pneumocystis carinii. The exact nature of its antiprotozoal action is unknown. in vitro studies with mammalian tissues and the protozoan Crithidia oncopelti indicate that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids and proteins. Little is known about the drug's pharmacokinetics. The medication is also useful in Leishmaniasis and in prophylaxis against sleeping sickness caused by Trypanosoma brucei gambiense. Hydration before treatment lessens the incidence and severity of side effects, which include liver or kidney dysfunction, hypertension, hypotension, hypoglycemia, hypocalemia, leukopenia, thrombcytopenia, anemia, and allergic reaction. It is generally well-tolerated.

Pentamide Absorption

Absorbed poorly through the gastrointestinal tract and is usually administered parenterally.

Pentamide side effects and Toxicity

Symptoms of overdose include pain, nausea, anorexia, hypotension, fever, rash, bad taste in mouth, confusion/hallucinations, dizziness, and diarrhea.

Pentamide Patient Information

No information avaliable

Pentamide Organisms Affected

Pneumocystis carinii