Pentacarinat

Pentacarinat Brand names, Pentacarinat Analogs

Pentacarinat Brand Names Mixture

No information avaliable

Pentacarinat Chemical_Formula

C₁₉H₂₄N₄O₂

Pentacarinat RX_link

http://www.rxlist.com/cgi/generic3/pentam.htm

Pentacarinat fda sheet

Pentacarinat msds (material safety sheet)

Pentacarinat MSDS

Pentacarinat Synthesis Reference

No information avaliable

Pentacarinat Molecular Weight

340.42 g/mol

Pentacarinat Melting Point

186.0 ^oC (decomposes)

Pentacarinat H₂O Solubility

Complete

Pentacarinat State

Solid

Pentacarinat LogP

3.28

Pentacarinat Dosage Forms

Powder for solution

Pentacarinat Indication

For the treatment of pneumonia due to Pneumocystis carinii.

Pentacarinat Pharmacology

Pentamidine is an antiprotozoal agent. It is an aromatic diamidine, and is known to have activity against Pneumocystis carinii. The exact nature of its antiprotozoal action is unknown. in vitro studies with mammalian tissues and the protozoan Crithidia oncopelti indicate that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids and proteins. Little is known about the drug's pharmacokinetics. The medication is also useful in Leishmaniasis and in prophylaxis against sleeping sickness caused by Trypanosoma brucei gambiense. Hydration before treatment lessens the incidence and severity of side effects, which include liver or kidney dysfunction, hypertension, hypotension, hypoglycemia, hypocalemia, leukopenia, thrombcytopenia, anemia, and allergic reaction. It is generally well-tolerated.

Pentacarinat Absorption

Absorbed poorly through the gastrointestinal tract and is usually administered parenterally.

Pentacarinat side effects and Toxicity

Symptoms of overdose include pain, nausea, anorexia, hypotension, fever, rash, bad taste in mouth, confusion/hallucinations, dizziness, and diarrhea.

Pentacarinat Patient Information