Pentam 300
Pentam 300 Brand names, Pentam 300 Analogs
Pentam 300 Brand Names Mixture
- No information avaliable
Pentam 300 Chemical_Formula
C19H24N4O2
Pentam 300 RX_link
http://www.rxlist.com/cgi/generic3/pentam.htm
Pentam 300 fda sheet
Pentam 300 msds (material safety sheet)
Pentam 300 Synthesis Reference
No information avaliable
Pentam 300 Molecular Weight
340.42 g/mol
Pentam 300 Melting Point
186.0 oC (decomposes)
Pentam 300 H2O Solubility
Complete
Pentam 300 State
Solid
Pentam 300 LogP
3.28
Pentam 300 Dosage Forms
Powder for solution
Pentam 300 Indication
For the treatment of pneumonia due to Pneumocystis carinii.
Pentam 300 Pharmacology
Pentamidine is an antiprotozoal agent. It is an aromatic diamidine, and is known to have activity against Pneumocystis carinii. The exact nature of its antiprotozoal action is unknown. in vitro studies with mammalian tissues and the protozoan Crithidia oncopelti indicate that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids and proteins. Little is known about the drug's pharmacokinetics. The medication is also useful in Leishmaniasis and in prophylaxis against sleeping sickness caused by Trypanosoma brucei gambiense. Hydration before treatment lessens the incidence and severity of side effects, which include liver or kidney dysfunction, hypertension, hypotension, hypoglycemia, hypocalemia, leukopenia, thrombcytopenia, anemia, and allergic reaction. It is generally well-tolerated.
Pentam 300 Absorption
Absorbed poorly through the gastrointestinal tract and is usually administered parenterally.
Pentam 300 side effects and Toxicity
Symptoms of overdose include pain, nausea, anorexia, hypotension, fever, rash, bad taste in mouth, confusion/hallucinations, dizziness, and diarrhea.
Pentam 300 Patient Information
No information avaliable
Pentam 300 Organisms Affected
Pneumocystis carinii
