Oxytyramine

Oxytyramine Brand names, Oxytyramine Analogs

Oxytyramine Brand Names Mixture

No information avaliable

Oxytyramine Chemical_Formula

C₈H₁₁NO₂

Oxytyramine RX_link

http://www.rxlist.com/cgi/generic3/dopamine.htm

Oxytyramine fda sheet

Oxytyramine msds (material safety sheet)

Oxytyramine MSDS

Oxytyramine Synthesis Reference

No information avaliable

Oxytyramine Molecular Weight

153.178 g/mol

Oxytyramine Melting Point

82.5 ^oC

Oxytyramine H₂O Solubility

600 g/L

Oxytyramine State

Solid

Oxytyramine LogP

0.548

Oxytyramine Dosage Forms

Solution

Oxytyramine Indication

For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Oxytyramine Pharmacology

Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA). It is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system, especially in the nigrostriatal tract, and in a few peripheral sympathetic nerves. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings.

Oxytyramine Absorption

Dopamine is rapidly absorbed from the small intestine.

Oxytyramine side effects and Toxicity

LD₅₀ oral mice = 1460 mg/kg, LD₅₀ oral rats = 1780 mg/kg. Spasm or closing of eyelids, nausea, vomiting, cardiac arrhythmias, involuntary movements of the body including the face, tongue, arms, hand, head, and upper body; hypotension, haemolytic anaemia, urinary retention, duodenal ulcer, sialorrhea, ataxia, abdominal pain, dry mouth, nightmares, tachypnoea, bruxism, confusion, and insomnia.

Oxytyramine Patient Information