Revimine
Brand names,
Revimine
Analogs
Revimine
Brand Names Mixture
Revimine
Chemical_Formula
C8H11NO2
Revimine
RX_link
http://www.rxlist.com/cgi/generic3/dopamine.htm
Revimine
fda sheet
Revimine
msds (material safety sheet)
Revimine
Synthesis Reference
No information avaliable
Revimine
Molecular Weight
153.178 g/mol
Revimine
Melting Point
82.5 oC
Revimine
H2O Solubility
600 g/L
Revimine
State
Solid
Revimine
LogP
0.548
Revimine
Dosage Forms
Solution
Revimine
Indication
For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure
Revimine
Pharmacology
Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA). It is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system, especially in the nigrostriatal tract, and in a few peripheral sympathetic nerves. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings.
Revimine
Absorption
Dopamine is rapidly absorbed from the small intestine.
Revimine
side effects and Toxicity
LD50 oral mice = 1460 mg/kg, LD50 oral rats = 1780 mg/kg. Spasm or closing of eyelids, nausea, vomiting, cardiac arrhythmias, involuntary movements of the body including the face, tongue, arms, hand, head, and upper body; hypotension, haemolytic anaemia, urinary retention, duodenal ulcer, sialorrhea, ataxia, abdominal pain, dry mouth, nightmares, tachypnoea, bruxism, confusion, and insomnia.
Revimine
Patient Information
No information avaliable
Revimine
Organisms Affected
Humans and other mammals