Hydroxytyramine

Hydroxytyramine Brand names, Hydroxytyramine Analogs

Hydroxytyramine Brand Names Mixture

No information avaliable

Hydroxytyramine Chemical_Formula

C₈H₁₁NO₂

Hydroxytyramine RX_link

http://www.rxlist.com/cgi/generic3/dopamine.htm

Hydroxytyramine fda sheet

Hydroxytyramine msds (material safety sheet)

Hydroxytyramine MSDS

Hydroxytyramine Synthesis Reference

No information avaliable

Hydroxytyramine Molecular Weight

153.178 g/mol

Hydroxytyramine Melting Point

82.5 ^oC

Hydroxytyramine H₂O Solubility

600 g/L

Hydroxytyramine State

Solid

Hydroxytyramine LogP

0.548

Hydroxytyramine Dosage Forms

Solution

Hydroxytyramine Indication

For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Hydroxytyramine Pharmacology

Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA). It is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system, especially in the nigrostriatal tract, and in a few peripheral sympathetic nerves. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings.

Hydroxytyramine Absorption

Dopamine is rapidly absorbed from the small intestine.

Hydroxytyramine side effects and Toxicity

LD₅₀ oral mice = 1460 mg/kg, LD₅₀ oral rats = 1780 mg/kg. Spasm or closing of eyelids, nausea, vomiting, cardiac arrhythmias, involuntary movements of the body including the face, tongue, arms, hand, head, and upper body; hypotension, haemolytic anaemia, urinary retention, duodenal ulcer, sialorrhea, ataxia, abdominal pain, dry mouth, nightmares, tachypnoea, bruxism, confusion, and insomnia.

Hydroxytyramine Patient Information