Oxytrol
Brand names,
Oxytrol
Analogs
Oxytrol
Brand Names Mixture
Oxytrol
Chemical_Formula
C22H31NO3
Oxytrol
RX_link
http://www.rxlist.com/cgi/generic/ditropan.htm
Oxytrol
fda sheet
Oxytrol
msds (material safety sheet)
Oxytrol
Synthesis Reference
Brit. pat. 940540 (1963 to Mead Johnson)
Oxytrol
Molecular Weight
357.486 g/mol
Oxytrol
Melting Point
129-130 oC
Oxytrol
H2O Solubility
No information avaliable
Oxytrol
State
Solid
Oxytrol
LogP
4.683
Oxytrol
Dosage Forms
Patch; Syrup; Tablet; Tablet (extended-release)
Oxytrol
Indication
For the treatment of overactive bladder.
Oxytrol
Pharmacology
Oxybutynin is an antispasmodic, anticholinergic agent indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. Oxybutynin relaxes bladder smooth muscle. Oxybutynin exhibits only one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. Antimuscarinic activity resides predominantly in the R-isomer.
Oxytrol
Absorption
Rapidly absorbed from gastrointestinal tract.
Oxytrol
side effects and Toxicity
LD50=1220 mg/kg (Orally in rats, Goldenthal)
Oxytrol
Patient Information
PATIENT INFORMATION
Patient should be informed that oxybutynin may produce drowsiness or blurred vision. Alcohal may enhance the drowsiness caused by anticholinergic agents. Fever and heat stroke can occur while anticholinergics are administered in the presence of high environmental temparature. Medication should be taken with the aid of liquids at approximately the same time each day. Patients should not chew, divide, or crush tablets.
Oxytrol
Organisms Affected
Humans and other mammals