Oxybutynin Hydrochloride
Oxybutynin Hydrochloride Brand names, Oxybutynin Hydrochloride Analogs
Oxybutynin Hydrochloride Brand Names Mixture
- No information avaliable
Oxybutynin Hydrochloride Chemical_Formula
C22H31NO3
Oxybutynin Hydrochloride RX_link
http://www.rxlist.com/cgi/generic/ditropan.htm
Oxybutynin Hydrochloride fda sheet
Oxybutynin Hydrochloride msds (material safety sheet)
Oxybutynin Hydrochloride Synthesis Reference
Brit. pat. 940540 (1963 to Mead Johnson)
Oxybutynin Hydrochloride Molecular Weight
357.486 g/mol
Oxybutynin Hydrochloride Melting Point
129-130 oC
Oxybutynin Hydrochloride H2O Solubility
No information avaliable
Oxybutynin Hydrochloride State
Solid
Oxybutynin Hydrochloride LogP
4.683
Oxybutynin Hydrochloride Dosage Forms
Patch; Syrup; Tablet; Tablet (extended-release)
Oxybutynin Hydrochloride Indication
For the treatment of overactive bladder.
Oxybutynin Hydrochloride Pharmacology
Oxybutynin is an antispasmodic, anticholinergic agent indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. Oxybutynin relaxes bladder smooth muscle. Oxybutynin exhibits only one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. Antimuscarinic activity resides predominantly in the R-isomer.
Oxybutynin Hydrochloride Absorption
Rapidly absorbed from gastrointestinal tract.
Oxybutynin Hydrochloride side effects and Toxicity
LD50=1220 mg/kg (Orally in rats, Goldenthal)
Oxybutynin Hydrochloride Patient Information
PATIENT INFORMATION
Patient should be informed that oxybutynin may produce drowsiness or blurred vision. Alcohal may enhance the drowsiness caused by anticholinergic agents. Fever and heat stroke can occur while anticholinergics are administered in the presence of high environmental temparature. Medication should be taken with the aid of liquids at approximately the same time each day. Patients should not chew, divide, or crush tablets.
Patient should be informed that oxybutynin may produce drowsiness or blurred vision. Alcohal may enhance the drowsiness caused by anticholinergic agents. Fever and heat stroke can occur while anticholinergics are administered in the presence of high environmental temparature. Medication should be taken with the aid of liquids at approximately the same time each day. Patients should not chew, divide, or crush tablets.
Oxybutynin Hydrochloride Organisms Affected
Humans and other mammals
