PharmacyCodes



Oxibutyninum en es it fr

Oxibutyninum Brand names, Oxibutyninum Analogs

Oxibutyninum Brand Names Mixture

  • No information avaliable

Oxibutyninum Chemical_Formula

C22H31NO3

Oxibutyninum RX_link

http://www.rxlist.com/cgi/generic/ditropan.htm

Oxibutyninum fda sheet

Oxibutyninum FDA

Oxibutyninum msds (material safety sheet)

Oxibutyninum MSDS

Oxibutyninum Synthesis Reference

Brit. pat. 940540 (1963 to Mead Johnson)

Oxibutyninum Molecular Weight

357.486 g/mol

Oxibutyninum Melting Point

129-130 oC

Oxibutyninum H2O Solubility

No information avaliable

Oxibutyninum State

Solid

Oxibutyninum LogP

4.683

Oxibutyninum Dosage Forms

Patch; Syrup; Tablet; Tablet (extended-release)

Oxibutyninum Indication

For the treatment of overactive bladder.

Oxibutyninum Pharmacology

Oxybutynin is an antispasmodic, anticholinergic agent indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. Oxybutynin relaxes bladder smooth muscle. Oxybutynin exhibits only one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. Antimuscarinic activity resides predominantly in the R-isomer.

Oxibutyninum Absorption

Rapidly absorbed from gastrointestinal tract.

Oxibutyninum side effects and Toxicity

LD50=1220 mg/kg (Orally in rats, Goldenthal)

Oxibutyninum Patient Information

PATIENT INFORMATION
Patient should be informed that oxybutynin may produce drowsiness or blurred vision. Alcohal may enhance the drowsiness caused by anticholinergic agents. Fever and heat stroke can occur while anticholinergics are administered in the presence of high environmental temparature. Medication should be taken with the aid of liquids at approximately the same time each day. Patients should not chew, divide, or crush tablets.

Oxibutyninum Organisms Affected

Humans and other mammals