Ditropan Xl
Brand names,
Ditropan Xl
Analogs
Ditropan Xl
Brand Names Mixture
Ditropan Xl
Chemical_Formula
C22H31NO3
Ditropan Xl
RX_link
http://www.rxlist.com/cgi/generic/ditropan.htm
Ditropan Xl
fda sheet
Ditropan Xl
msds (material safety sheet)
Ditropan Xl
Synthesis Reference
Brit. pat. 940540 (1963 to Mead Johnson)
Ditropan Xl
Molecular Weight
357.486 g/mol
Ditropan Xl
Melting Point
129-130 oC
Ditropan Xl
H2O Solubility
No information avaliable
Ditropan Xl
State
Solid
Ditropan Xl
LogP
4.683
Ditropan Xl
Dosage Forms
Patch; Syrup; Tablet; Tablet (extended-release)
Ditropan Xl
Indication
For the treatment of overactive bladder.
Ditropan Xl
Pharmacology
Oxybutynin is an antispasmodic, anticholinergic agent indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. Oxybutynin relaxes bladder smooth muscle. Oxybutynin exhibits only one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. Antimuscarinic activity resides predominantly in the R-isomer.
Ditropan Xl
Absorption
Rapidly absorbed from gastrointestinal tract.
Ditropan Xl
side effects and Toxicity
LD50=1220 mg/kg (Orally in rats, Goldenthal)
Ditropan Xl
Patient Information
PATIENT INFORMATION
Patient should be informed that oxybutynin may produce drowsiness or blurred vision. Alcohal may enhance the drowsiness caused by anticholinergic agents. Fever and heat stroke can occur while anticholinergics are administered in the presence of high environmental temparature. Medication should be taken with the aid of liquids at approximately the same time each day. Patients should not chew, divide, or crush tablets.
Ditropan Xl
Organisms Affected
Humans and other mammals