Estrone-sulfate en es it fr

Estrone-sulfate Brand names, Estrone-sulfate Analogs

Estrone-sulfate Brand Names Mixture

  • Prempro (conjugated estrogens + medroxyprogesteron)

Estrone-sulfate Chemical_Formula


Estrone-sulfate RX_link

Estrone-sulfate fda sheet

Estrone-sulfate FDA

Estrone-sulfate msds (material safety sheet)

Estrone-sulfate MSDS

Estrone-sulfate Synthesis Reference

Bates, Cohen, U.S. Pat. 2,565,115 (1951)

Estrone-sulfate Molecular Weight

372.412 g/mol

Estrone-sulfate Melting Point

173 oC

Estrone-sulfate H2O Solubility

0.0036 mg/ml

Estrone-sulfate State


Estrone-sulfate LogP

No information avaliable

Estrone-sulfate Dosage Forms

Tablet; Injection; Vaginal cream; Topical gel

Estrone-sulfate Indication

For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and Advanced androgen-dependent carcinoma of the prostate (for palliation only)

Estrone-sulfate Pharmacology

Conjugated estrogens, a mixture of the water soluble salts of sulfate esters from estrone, equilin, 17 α-dihydroequilin, and other related steroids, may be derived from pregnant equine urine or yam and soy plants. Estrogens are important in the development and maintenance of the female reproductive system and secondary sex characteristics. They promote growth and development of the vagina, uterus, and fallopian tubes, and enlargement of the breasts. Indirectly, they contribute to the shaping of the skeleton, maintenance of tone and elasticity of urogenital structures, changes in the epiphyses of the long bones that allow for the pubertal growth spurt and its termination, growth of axillary and pubic hair, and pigmentation of the nipples and genitals. Decline of estrogenic activity at the end of the menstrual cycle can bring on menstruation, although the cessation of progesterone secretion is the most important factor in the mature ovulatory cycle. However, in the preovulatory or nonovulatory cycle, estrogen is the primary determinant in the onset of menstruation. Estrogens also affect the release of pituitary gonadotropins. The pharmacologic effects of conjugated estrogens are similar to those of endogenous estrogens.

Estrone-sulfate Absorption

Well absorbed

Estrone-sulfate side effects and Toxicity

Nausea and vomiting

Estrone-sulfate Patient Information

Estrone-sulfate Organisms Affected

Humans and other mammals