Oestrone Sulphate en es it fr

Oestrone Sulphate Brand names, Oestrone Sulphate Analogs

Oestrone Sulphate Brand Names Mixture

  • Prempro (conjugated estrogens + medroxyprogesteron)

Oestrone Sulphate Chemical_Formula


Oestrone Sulphate RX_link


Oestrone Sulphate fda sheet

Oestrone_Sulphate FDA

Oestrone Sulphate msds (material safety sheet)

Oestrone_Sulphate MSDS

Oestrone Sulphate Synthesis Reference

Bates, Cohen, U.S. Pat. 2,565,115 (1951)

Oestrone Sulphate Molecular Weight

372.412 g/mol

Oestrone Sulphate Melting Point

173 oC

Oestrone Sulphate H2O Solubility

0.0036 mg/ml

Oestrone Sulphate State


Oestrone Sulphate LogP

No information avaliable

Oestrone Sulphate Dosage Forms

Tablet; Injection; Vaginal cream; Topical gel

Oestrone Sulphate Indication

For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and Advanced androgen-dependent carcinoma of the prostate (for palliation only)

Oestrone Sulphate Pharmacology

Conjugated estrogens, a mixture of the water soluble salts of sulfate esters from estrone, equilin, 17 α-dihydroequilin, and other related steroids, may be derived from pregnant equine urine or yam and soy plants. Estrogens are important in the development and maintenance of the female reproductive system and secondary sex characteristics. They promote growth and development of the vagina, uterus, and fallopian tubes, and enlargement of the breasts. Indirectly, they contribute to the shaping of the skeleton, maintenance of tone and elasticity of urogenital structures, changes in the epiphyses of the long bones that allow for the pubertal growth spurt and its termination, growth of axillary and pubic hair, and pigmentation of the nipples and genitals. Decline of estrogenic activity at the end of the menstrual cycle can bring on menstruation, although the cessation of progesterone secretion is the most important factor in the mature ovulatory cycle. However, in the preovulatory or nonovulatory cycle, estrogen is the primary determinant in the onset of menstruation. Estrogens also affect the release of pituitary gonadotropins. The pharmacologic effects of conjugated estrogens are similar to those of endogenous estrogens.

Oestrone Sulphate Absorption

Well absorbed

Oestrone Sulphate side effects and Toxicity

Nausea and vomiting

Oestrone Sulphate Patient Information

Oestrone Sulphate Organisms Affected

Humans and other mammals