Estrone Sulphate en es it fr

Estrone Sulphate Brand names, Estrone Sulphate Analogs

Estrone Sulphate Brand Names Mixture

  • Prempro (conjugated estrogens + medroxyprogesteron)

Estrone Sulphate Chemical_Formula


Estrone Sulphate RX_link

Estrone Sulphate fda sheet

Estrone_Sulphate FDA

Estrone Sulphate msds (material safety sheet)

Estrone_Sulphate MSDS

Estrone Sulphate Synthesis Reference

Bates, Cohen, U.S. Pat. 2,565,115 (1951)

Estrone Sulphate Molecular Weight

372.412 g/mol

Estrone Sulphate Melting Point

173 oC

Estrone Sulphate H2O Solubility

0.0036 mg/ml

Estrone Sulphate State


Estrone Sulphate LogP

No information avaliable

Estrone Sulphate Dosage Forms

Tablet; Injection; Vaginal cream; Topical gel

Estrone Sulphate Indication

For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and Advanced androgen-dependent carcinoma of the prostate (for palliation only)

Estrone Sulphate Pharmacology

Conjugated estrogens, a mixture of the water soluble salts of sulfate esters from estrone, equilin, 17 α-dihydroequilin, and other related steroids, may be derived from pregnant equine urine or yam and soy plants. Estrogens are important in the development and maintenance of the female reproductive system and secondary sex characteristics. They promote growth and development of the vagina, uterus, and fallopian tubes, and enlargement of the breasts. Indirectly, they contribute to the shaping of the skeleton, maintenance of tone and elasticity of urogenital structures, changes in the epiphyses of the long bones that allow for the pubertal growth spurt and its termination, growth of axillary and pubic hair, and pigmentation of the nipples and genitals. Decline of estrogenic activity at the end of the menstrual cycle can bring on menstruation, although the cessation of progesterone secretion is the most important factor in the mature ovulatory cycle. However, in the preovulatory or nonovulatory cycle, estrogen is the primary determinant in the onset of menstruation. Estrogens also affect the release of pituitary gonadotropins. The pharmacologic effects of conjugated estrogens are similar to those of endogenous estrogens.

Estrone Sulphate Absorption

Well absorbed

Estrone Sulphate side effects and Toxicity

Nausea and vomiting

Estrone Sulphate Patient Information

Estrone Sulphate Organisms Affected

Humans and other mammals