OMEP

OMEP Brand names, OMEP Analogs

OMEP Brand Names Mixture

No information avaliable

OMEP Chemical_Formula

C₁₇H₁₉N₃O₃S

OMEP RX_link

http://www.rxlist.com/cgi/generic3/esomeprazole.htm

OMEP fda sheet

OMEP FDA

OMEP msds (material safety sheet)

OMEP Synthesis Reference

No information avaliable

OMEP Molecular Weight

345.417 g/mol

OMEP Melting Point

155 ^oC

OMEP H₂O Solubility

Very slightly soluble in water

OMEP State

Solid

OMEP LogP

1.078

OMEP Dosage Forms

Tablet (delayed-release); Delayed-release capsules; IV injection solution; IV iufusion solution

OMEP Indication

For the treatment of acid-reflux disorders (GERD) and peptic ulcer disease

OMEP Pharmacology

Esomeprazole is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. Esomeprazole belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H⁺/K⁺ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Esomeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.

OMEP Absorption

90%

OMEP side effects and Toxicity

Blurred vision, confusion, drowsiness, dry mouthflushingheadache, nausea, rapid heartbeat, sweating

OMEP Patient Information