Norcodine, N-Methyl
Norcodine, N-Methyl Brand names, Norcodine, N-Methyl Analogs
Norcodine, N-Methyl Brand Names Mixture
- No information avaliable
Norcodine, N-Methyl Chemical_Formula
C18H21NO3
Norcodine, N-Methyl RX_link
http://www.rxlist.com/cgi/generic/codphos.htm
Norcodine, N-Methyl fda sheet
Norcodine, N-Methyl msds (material safety sheet)
Norcodine, N-Methyl Synthesis Reference
Goto, Yamamoto, Proc. Japan Acad. 30, 769 (1954)
Norcodine, N-Methyl Molecular Weight
299.364 g/mol
Norcodine, N-Methyl Melting Point
154 - 156 oC
Norcodine, N-Methyl H2O Solubility
<0.1 g/100 mL
Norcodine, N-Methyl State
solid
Norcodine, N-Methyl LogP
1.809
Norcodine, N-Methyl Dosage Forms
Oral solution; Tablet
Norcodine, N-Methyl Indication
For treatment and management of pain (Systemic), also used as an Antidiarrheal and as a cough suppressant.
Norcodine, N-Methyl Pharmacology
Codeine, an opiate agonist in the CNS, is similar to other phenanthrene derivatives such as morphine. Codeine, in combination with guaifenesin or iodinated glycerol, is used as a cough suppressant and, as a single agent or in combination with acetaminophen or other products, is used for pain control and as an antidiarrheal agent.
Norcodine, N-Methyl Absorption
well absorbed
Norcodine, N-Methyl side effects and Toxicity
Respiratory depression, sedation and miosis and common symptoms of overdose. Other symptoms include nausea, vomiting, skeletal muscle flaccidity, bradycardia, hypotension, and cool, clammy skin. Apnea and death may ensue
Norcodine, N-Methyl Patient Information
Codeine may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, s.c. as driving a car or operating machinery. Codeine in combination with other narcotic analgesics, phenothiazines, sedative hypnotics, and alcohol has additive depressant effects.
Norcodine, N-Methyl Organisms Affected
Humans and other mammals
