Morphine monomethyl ether
Brand names,
Morphine monomethyl ether
Analogs
Morphine monomethyl ether
Brand Names Mixture
Morphine monomethyl ether
Chemical_Formula
C18H21NO3
Morphine monomethyl ether
RX_link
http://www.rxlist.com/cgi/generic/codphos.htm
Morphine monomethyl ether
fda sheet
Morphine monomethyl ether
msds (material safety sheet)
Morphine monomethyl ether
Synthesis Reference
Goto, Yamamoto, Proc. Japan Acad. 30, 769 (1954)
Morphine monomethyl ether
Molecular Weight
299.364 g/mol
Morphine monomethyl ether
Melting Point
154 - 156 oC
Morphine monomethyl ether
H2O Solubility
<0.1 g/100 mL
Morphine monomethyl ether
State
solid
Morphine monomethyl ether
LogP
1.809
Morphine monomethyl ether
Dosage Forms
Oral solution; Tablet
Morphine monomethyl ether
Indication
For treatment and management of pain (Systemic), also used as an Antidiarrheal and as a cough suppressant.
Morphine monomethyl ether
Pharmacology
Codeine, an opiate agonist in the CNS, is similar to other phenanthrene derivatives such as morphine. Codeine, in combination with guaifenesin or iodinated glycerol, is used as a cough suppressant and, as a single agent or in combination with acetaminophen or other products, is used for pain control and as an antidiarrheal agent.
Morphine monomethyl ether
Absorption
well absorbed
Morphine monomethyl ether
side effects and Toxicity
Respiratory depression, sedation and miosis and common symptoms of overdose. Other symptoms include nausea, vomiting, skeletal muscle flaccidity, bradycardia, hypotension, and cool, clammy skin. Apnea and death may ensue
Morphine monomethyl ether
Patient Information
Codeine may impair the mental and/or physical abilities required for the performance of potentially hazardous
tasks, s.c. as driving a car or operating machinery. Codeine in combination with other narcotic analgesics,
phenothiazines, sedative hypnotics, and alcohol has additive depressant effects.
Morphine monomethyl ether
Organisms Affected
Humans and other mammals