L-Codeine
L-Codeine Brand names, L-Codeine Analogs
L-Codeine Brand Names Mixture
- No information avaliable
L-Codeine Chemical_Formula
C18H21NO3
L-Codeine RX_link
http://www.rxlist.com/cgi/generic/codphos.htm
L-Codeine fda sheet
L-Codeine msds (material safety sheet)
L-Codeine Synthesis Reference
Goto, Yamamoto, Proc. Japan Acad. 30, 769 (1954)
L-Codeine Molecular Weight
299.364 g/mol
L-Codeine Melting Point
154 - 156 oC
L-Codeine H2O Solubility
<0.1 g/100 mL
L-Codeine State
solid
L-Codeine LogP
1.809
L-Codeine Dosage Forms
Oral solution; Tablet
L-Codeine Indication
For treatment and management of pain (Systemic), also used as an Antidiarrheal and as a cough suppressant.
L-Codeine Pharmacology
Codeine, an opiate agonist in the CNS, is similar to other phenanthrene derivatives such as morphine. Codeine, in combination with guaifenesin or iodinated glycerol, is used as a cough suppressant and, as a single agent or in combination with acetaminophen or other products, is used for pain control and as an antidiarrheal agent.
L-Codeine Absorption
well absorbed
L-Codeine side effects and Toxicity
Respiratory depression, sedation and miosis and common symptoms of overdose. Other symptoms include nausea, vomiting, skeletal muscle flaccidity, bradycardia, hypotension, and cool, clammy skin. Apnea and death may ensue
L-Codeine Patient Information
Codeine may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, s.c. as driving a car or operating machinery. Codeine in combination with other narcotic analgesics, phenothiazines, sedative hypnotics, and alcohol has additive depressant effects.
L-Codeine Organisms Affected
Humans and other mammals
