Methylmorphine
Brand names,
Methylmorphine
Analogs
Methylmorphine
Brand Names Mixture
Methylmorphine
Chemical_Formula
C18H21NO3
Methylmorphine
RX_link
http://www.rxlist.com/cgi/generic/codphos.htm
Methylmorphine
fda sheet
Methylmorphine
msds (material safety sheet)
Methylmorphine
Synthesis Reference
Goto, Yamamoto, Proc. Japan Acad. 30, 769 (1954)
Methylmorphine
Molecular Weight
299.364 g/mol
Methylmorphine
Melting Point
154 - 156 oC
Methylmorphine
H2O Solubility
<0.1 g/100 mL
Methylmorphine
State
solid
Methylmorphine
LogP
1.809
Methylmorphine
Dosage Forms
Oral solution; Tablet
Methylmorphine
Indication
For treatment and management of pain (Systemic), also used as an Antidiarrheal and as a cough suppressant.
Methylmorphine
Pharmacology
Codeine, an opiate agonist in the CNS, is similar to other phenanthrene derivatives such as morphine. Codeine, in combination with guaifenesin or iodinated glycerol, is used as a cough suppressant and, as a single agent or in combination with acetaminophen or other products, is used for pain control and as an antidiarrheal agent.
Methylmorphine
Absorption
well absorbed
Methylmorphine
side effects and Toxicity
Respiratory depression, sedation and miosis and common symptoms of overdose. Other symptoms include nausea, vomiting, skeletal muscle flaccidity, bradycardia, hypotension, and cool, clammy skin. Apnea and death may ensue
Methylmorphine
Patient Information
Codeine may impair the mental and/or physical abilities required for the performance of potentially hazardous
tasks, s.c. as driving a car or operating machinery. Codeine in combination with other narcotic analgesics,
phenothiazines, sedative hypnotics, and alcohol has additive depressant effects.
Methylmorphine
Organisms Affected
Humans and other mammals