Coducept
Brand names,
Coducept
Analogs
Coducept
Brand Names Mixture
Coducept
Chemical_Formula
C18H21NO3
Coducept
RX_link
http://www.rxlist.com/cgi/generic/codphos.htm
Coducept
fda sheet
Coducept
msds (material safety sheet)
Coducept
Synthesis Reference
Goto, Yamamoto, Proc. Japan Acad. 30, 769 (1954)
Coducept
Molecular Weight
299.364 g/mol
Coducept
Melting Point
154 - 156 oC
Coducept
H2O Solubility
<0.1 g/100 mL
Coducept
State
solid
Coducept
LogP
1.809
Coducept
Dosage Forms
Oral solution; Tablet
Coducept
Indication
For treatment and management of pain (Systemic), also used as an Antidiarrheal and as a cough suppressant.
Coducept
Pharmacology
Codeine, an opiate agonist in the CNS, is similar to other phenanthrene derivatives such as morphine. Codeine, in combination with guaifenesin or iodinated glycerol, is used as a cough suppressant and, as a single agent or in combination with acetaminophen or other products, is used for pain control and as an antidiarrheal agent.
Coducept
Absorption
well absorbed
Coducept
side effects and Toxicity
Respiratory depression, sedation and miosis and common symptoms of overdose. Other symptoms include nausea, vomiting, skeletal muscle flaccidity, bradycardia, hypotension, and cool, clammy skin. Apnea and death may ensue
Coducept
Patient Information
Codeine may impair the mental and/or physical abilities required for the performance of potentially hazardous
tasks, s.c. as driving a car or operating machinery. Codeine in combination with other narcotic analgesics,
phenothiazines, sedative hypnotics, and alcohol has additive depressant effects.
Coducept
Organisms Affected
Humans and other mammals