Norco
Brand names,
Norco
Analogs
Norco
Brand Names Mixture
Norco
Chemical_Formula
C18H21NO3
Norco
RX_link
http://www.rxlist.com/cgi/generic/codphos.htm
Norco
fda sheet
Norco
msds (material safety sheet)
Norco
Synthesis Reference
Goto, Yamamoto, Proc. Japan Acad. 30, 769 (1954)
Norco
Molecular Weight
299.364 g/mol
Norco
Melting Point
154 - 156 oC
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H2O Solubility
<0.1 g/100 mL
Norco
State
solid
Norco
LogP
1.809
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Dosage Forms
Oral solution; Tablet
Norco
Indication
For treatment and management of pain (Systemic), also used as an Antidiarrheal and as a cough suppressant.
Norco
Pharmacology
Codeine, an opiate agonist in the CNS, is similar to other phenanthrene derivatives such as morphine. Codeine, in combination with guaifenesin or iodinated glycerol, is used as a cough suppressant and, as a single agent or in combination with acetaminophen or other products, is used for pain control and as an antidiarrheal agent.
Norco
Absorption
well absorbed
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side effects and Toxicity
Respiratory depression, sedation and miosis and common symptoms of overdose. Other symptoms include nausea, vomiting, skeletal muscle flaccidity, bradycardia, hypotension, and cool, clammy skin. Apnea and death may ensue
Norco
Patient Information
Codeine may impair the mental and/or physical abilities required for the performance of potentially hazardous
tasks, s.c. as driving a car or operating machinery. Codeine in combination with other narcotic analgesics,
phenothiazines, sedative hypnotics, and alcohol has additive depressant effects.
Norco
Organisms Affected
Humans and other mammals