Nisotin
Brand names,
Nisotin
Analogs
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Brand Names Mixture
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Chemical_Formula
C16H16ClNO3
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RX_link
http://www.rxlist.com/cgi/generic3/fenoldopam.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
305.756 g/mol
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Melting Point
No information avaliable
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H2O Solubility
4000 mg/L
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State
Solid
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LogP
2.937
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Dosage Forms
Solution
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Indication
For the in-hospital, short-term (up to 48 hours) management of severe hypertension when rapid, but quickly reversible, emergency reduction of blood pressure is clinically indicated, including malignant hypertension with deteriorating end-organ function.
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Pharmacology
Fenoldopam antagonizes D1-like dopamine receptors, binds to α2-adrenoceptors, increasing renal blood flow.
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Absorption
No information avaliable
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side effects and Toxicity
The most likely reaction of overdose would be excessive hypotension which should be treated with drug discontinuation and appropriate supportive measures.
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals