Nicotion
Brand names,
Nicotion
Analogs
Nicotion
Brand Names Mixture
Nicotion
Chemical_Formula
C16H16ClNO3
Nicotion
RX_link
http://www.rxlist.com/cgi/generic3/fenoldopam.htm
Nicotion
fda sheet
Nicotion
msds (material safety sheet)
Nicotion
Synthesis Reference
No information avaliable
Nicotion
Molecular Weight
305.756 g/mol
Nicotion
Melting Point
No information avaliable
Nicotion
H2O Solubility
4000 mg/L
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State
Solid
Nicotion
LogP
2.937
Nicotion
Dosage Forms
Solution
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Indication
For the in-hospital, short-term (up to 48 hours) management of severe hypertension when rapid, but quickly reversible, emergency reduction of blood pressure is clinically indicated, including malignant hypertension with deteriorating end-organ function.
Nicotion
Pharmacology
Fenoldopam antagonizes D1-like dopamine receptors, binds to α2-adrenoceptors, increasing renal blood flow.
Nicotion
Absorption
No information avaliable
Nicotion
side effects and Toxicity
The most likely reaction of overdose would be excessive hypotension which should be treated with drug discontinuation and appropriate supportive measures.
Nicotion
Patient Information
No information avaliable
Nicotion
Organisms Affected
Humans and other mammals