Nisoldipine
Nisoldipine Brand names, Nisoldipine Analogs
Nisoldipine Brand Names Mixture
- No information avaliable
Nisoldipine Chemical_Formula
C20H24N2O6
Nisoldipine RX_link
http://www.rxlist.com/cgi/generic/nisoldipine.htm
Nisoldipine fda sheet
Nisoldipine msds (material safety sheet)
Nisoldipine Synthesis Reference
No information avaliable
Nisoldipine Molecular Weight
388.414 g/mol
Nisoldipine Melting Point
No information avaliable
Nisoldipine H2O Solubility
No information avaliable
Nisoldipine State
Solid
Nisoldipine LogP
3.475
Nisoldipine Dosage Forms
No information avaliable
Nisoldipine Indication
Hypertension
Nisoldipine Pharmacology
Nisoldipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nisoldipine is similar to other peripheral vasodilators. Nisoldipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Nisoldipine Absorption
No information avaliable
Nisoldipine side effects and Toxicity
No information avaliable
Nisoldipine Patient Information
Nisoldipine Organisms Affected
Humans and other mammals
