Nisoldipin
Nisoldipin Brand names, Nisoldipin Analogs
Nisoldipin Brand Names Mixture
- No information avaliable
Nisoldipin Chemical_Formula
C20H24N2O6
Nisoldipin RX_link
http://www.rxlist.com/cgi/generic/nisoldipine.htm
Nisoldipin fda sheet
Nisoldipin msds (material safety sheet)
Nisoldipin Synthesis Reference
No information avaliable
Nisoldipin Molecular Weight
388.414 g/mol
Nisoldipin Melting Point
No information avaliable
Nisoldipin H2O Solubility
No information avaliable
Nisoldipin State
Solid
Nisoldipin LogP
3.475
Nisoldipin Dosage Forms
No information avaliable
Nisoldipin Indication
Hypertension
Nisoldipin Pharmacology
Nisoldipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nisoldipine is similar to other peripheral vasodilators. Nisoldipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Nisoldipin Absorption
No information avaliable
Nisoldipin side effects and Toxicity
No information avaliable
Nisoldipin Patient Information
Nisoldipin Organisms Affected
Humans and other mammals
