Syscor
Syscor Brand names, Syscor Analogs
Syscor Brand Names Mixture
- No information avaliable
Syscor Chemical_Formula
C20H24N2O6
Syscor RX_link
http://www.rxlist.com/cgi/generic/nisoldipine.htm
Syscor fda sheet
Syscor msds (material safety sheet)
Syscor Synthesis Reference
No information avaliable
Syscor Molecular Weight
388.414 g/mol
Syscor Melting Point
No information avaliable
Syscor H2O Solubility
No information avaliable
Syscor State
Solid
Syscor LogP
3.475
Syscor Dosage Forms
No information avaliable
Syscor Indication
Hypertension
Syscor Pharmacology
Nisoldipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nisoldipine is similar to other peripheral vasodilators. Nisoldipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Syscor Absorption
No information avaliable
Syscor side effects and Toxicity
No information avaliable
Syscor Patient Information
Syscor Organisms Affected
Humans and other mammals
