Nisoldipinum [Inn-Latin]
Nisoldipinum [Inn-Latin] Brand names, Nisoldipinum [Inn-Latin] Analogs
Nisoldipinum [Inn-Latin] Brand Names Mixture
- No information avaliable
Nisoldipinum [Inn-Latin] Chemical_Formula
C20H24N2O6
Nisoldipinum [Inn-Latin] RX_link
http://www.rxlist.com/cgi/generic/nisoldipine.htm
Nisoldipinum [Inn-Latin] fda sheet
Nisoldipinum [Inn-Latin] msds (material safety sheet)
Nisoldipinum [Inn-Latin] Synthesis Reference
No information avaliable
Nisoldipinum [Inn-Latin] Molecular Weight
388.414 g/mol
Nisoldipinum [Inn-Latin] Melting Point
No information avaliable
Nisoldipinum [Inn-Latin] H2O Solubility
No information avaliable
Nisoldipinum [Inn-Latin] State
Solid
Nisoldipinum [Inn-Latin] LogP
3.475
Nisoldipinum [Inn-Latin] Dosage Forms
No information avaliable
Nisoldipinum [Inn-Latin] Indication
Hypertension
Nisoldipinum [Inn-Latin] Pharmacology
Nisoldipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nisoldipine is similar to other peripheral vasodilators. Nisoldipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Nisoldipinum [Inn-Latin] Absorption
No information avaliable
Nisoldipinum [Inn-Latin] side effects and Toxicity
No information avaliable
Nisoldipinum [Inn-Latin] Patient Information
Nisoldipinum [Inn-Latin] Organisms Affected
Humans and other mammals
![Nisoldipinum_[Inn-Latin]](/images/rx/APRD00635.gif)
