Nisocor
Nisocor Brand names, Nisocor Analogs
Nisocor Brand Names Mixture
- No information avaliable
Nisocor Chemical_Formula
C20H24N2O6
Nisocor RX_link
http://www.rxlist.com/cgi/generic/nisoldipine.htm
Nisocor fda sheet
Nisocor msds (material safety sheet)
Nisocor Synthesis Reference
No information avaliable
Nisocor Molecular Weight
388.414 g/mol
Nisocor Melting Point
No information avaliable
Nisocor H2O Solubility
No information avaliable
Nisocor State
Solid
Nisocor LogP
3.475
Nisocor Dosage Forms
No information avaliable
Nisocor Indication
Hypertension
Nisocor Pharmacology
Nisoldipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nisoldipine is similar to other peripheral vasodilators. Nisoldipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Nisocor Absorption
No information avaliable
Nisocor side effects and Toxicity
No information avaliable
Nisocor Patient Information
Nisocor Organisms Affected
Humans and other mammals
