Zadipina
Zadipina Brand names, Zadipina Analogs
Zadipina Brand Names Mixture
- No information avaliable
Zadipina Chemical_Formula
C20H24N2O6
Zadipina RX_link
http://www.rxlist.com/cgi/generic/nisoldipine.htm
Zadipina fda sheet
Zadipina msds (material safety sheet)
Zadipina Synthesis Reference
No information avaliable
Zadipina Molecular Weight
388.414 g/mol
Zadipina Melting Point
No information avaliable
Zadipina H2O Solubility
No information avaliable
Zadipina State
Solid
Zadipina LogP
3.475
Zadipina Dosage Forms
No information avaliable
Zadipina Indication
Hypertension
Zadipina Pharmacology
Nisoldipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nisoldipine is similar to other peripheral vasodilators. Nisoldipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Zadipina Absorption
No information avaliable
Zadipina side effects and Toxicity
No information avaliable
Zadipina Patient Information
Zadipina Organisms Affected
Humans and other mammals
