Naloxone
Brand names,
Naloxone
Analogs
Naloxone
Brand Names Mixture
Naloxone
Chemical_Formula
C19H21NO4
Naloxone
RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
Naloxone
fda sheet
Naloxone
msds (material safety sheet)
Naloxone
Synthesis Reference
No information avaliable
Naloxone
Molecular Weight
327.374 g/mol
Naloxone
Melting Point
200 - 205 oC
Naloxone
H2O Solubility
Soluble
Naloxone
State
Solid
Naloxone
LogP
1.464
Naloxone
Dosage Forms
Liquid
Naloxone
Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
Naloxone
Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
Naloxone
Absorption
Well absorbed following intramuscular injection.
Naloxone
side effects and Toxicity
No information avaliable
Naloxone
Patient Information
No information avaliable
Naloxone
Organisms Affected
Humans and other mammals